New Research In

Table of Contents

October 27, 2020; vol. 117 no. 43

This Week in PNAS

This week's research highlights

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In This Issue
PNAS October 27, 2020 117 (43) 26537-26538; https://doi.org/10.1073/iti4320117
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Opinion

Leading scientists discuss current issues

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Opinion: Cultural and linguistic diversities are underappreciated pillars of biodiversity
Front Matter
André Frainer, Tero Mustonen, Sutej Hugu, Tamara Andreeva, Elle-Maarit Arttijeff, Inka-Saara Arttijeff, Felipe Brizoela, Gabriela Coelho-de-Souza, Rafaela Biehl Printes, Evgenia Prokhorova, Salatou Sambou, Antoine Scherer, Vyacheslav Shadrin, and Gretta Pecl

PNAS October 27, 2020 117 (43) 26539-26543; first published October 7, 2020. https://doi.org/10.1073/pnas.2019469117
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Inner Workings

An over-the-shoulder look at scientists at work

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Inner Workings: Research sub buoys prospects for 3D map of marine microbial communities
Front Matter
Amy McDermott

PNAS October 27, 2020 117 (43) 26544-26547; first published October 7, 2020. https://doi.org/10.1073/pnas.2019245117
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QnAs

Interviews with leading scientific researchers and newsmakers

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QnAs with Richard N. Aslin
Brian Doctrow

PNAS October 27, 2020 117 (43) 26548-26549; first published October 14, 2020. https://doi.org/10.1073/pnas.2019998117

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Commentaries

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Visualizing ultrafast chemical dynamics with X-rays
Roseanne J. Sension

PNAS October 27, 2020 117 (43) 26550-26552; first published October 6, 2020. https://doi.org/10.1073/pnas.2017806117

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Spin cascade and doming in ferric hemes: Femtosecond X-ray absorption and X-ray emission studies
- Aug 26, 2020
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A novel spectroscopic window on conical intersections in biomolecules
Giulio Cerullo and Marco Garavelli

PNAS October 27, 2020 117 (43) 26553-26555; first published October 19, 2020. https://doi.org/10.1073/pnas.2018651117

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Visualizing conical intersection passages via vibronic coherence maps generated by stimulated ultrafast X-ray Raman signals
- Sep 14, 2020
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The hanging heart: How KRAS lures its prey to the membrane
Dirk Kessler and Darryl B. McConnell

PNAS October 27, 2020 117 (43) 26556-26558; first published September 30, 2020. https://doi.org/10.1073/pnas.2017730117

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Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane
- Sep 10, 2020
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America in pain, the nation’s well-being at stake
Nicole Maestas

PNAS October 27, 2020 117 (43) 26559-26561; first published October 19, 2020. https://doi.org/10.1073/pnas.2018650117

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Decoding the mystery of American pain reveals a warning for the future
- Sep 21, 2020
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Perspective

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Performance vs. competence in human–machine comparisons
Chaz Firestone

PNAS October 27, 2020 117 (43) 26562-26571; first published October 13, 2020. https://doi.org/10.1073/pnas.1905334117

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Letters

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An ill-posed boundary condition was inadvertently implemented when deriving the expression to characterize deformation of neurons
Brenda Farrell

PNAS October 27, 2020 117 (43) 26572-26573; first published October 13, 2020. https://doi.org/10.1073/pnas.2015950117

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Reply to Farrell: Experimental evidence is the ultimate judge for model assumptions
Tong Ling, Kevin C. Boyle, and Daniel Palanker

PNAS October 27, 2020 117 (43) 26574-26575; first published October 13, 2020. https://doi.org/10.1073/pnas.2017702117

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High-speed interferometric imaging reveals dynamics of neuronal deformation during the action potential
- Apr 27, 2020
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Airborne particulate matter and health effects on bees: A correlation does not indicate causation
Ilaria Negri, Giancarlo Capitani, and Marco Pellecchia

PNAS October 27, 2020 117 (43) 26576-26577; first published October 13, 2020. https://doi.org/10.1073/pnas.2017536117

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Reply to Negri et al.: Air pollution and health impacts on bees: Signs of causation
Geetha G. Thimmegowda, Axel Brockmann, Perundurai S. Dhandapany, and Shannon B. Olsson

PNAS October 27, 2020 117 (43) 26578-26579; first published October 13, 2020. https://doi.org/10.1073/pnas.2017972117

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A field-based quantitative analysis of sublethal effects of air pollution on pollinators
- Aug 10, 2020
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Physical Sciences

Applied Physical Sciences
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  Dissecting landscape art history with information theory
  
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  Byunghwee Lee, Min Kyung Seo, Daniel Kim, In-seob Shin, Maximilian Schich, Hawoong Jeong, and Seung Kee Han
  
  PNAS October 27, 2020 117 (43) 26580-26590; first published October 12, 2020. https://doi.org/10.1073/pnas.2011927117
  
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  The human quest for discovering mathematical beauty in the arts
  - Oct 23, 2020
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  The anomalies and criticality of liquid water
  Rui Shi and Hajime Tanaka
  
  PNAS October 27, 2020 117 (43) 26591-26599; first published October 15, 2020. https://doi.org/10.1073/pnas.2008426117
  
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Biophysics and Computational Biology
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  Mechanical design of apertures and the infolding of pollen grain
  Anže Božič and Antonio Šiber
  
  PNAS October 27, 2020 117 (43) 26600-26607; first published October 7, 2020. https://doi.org/10.1073/pnas.2011084117
  
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  Filtering input fluctuations in intensity and in time underlies stochastic transcriptional pulses without feedback
  Alberto Stefano Sassi, Mayra Garcia-Alcala, Mark J. Kim, Philippe Cluzel, and Yuhai Tu
  
  PNAS October 27, 2020 117 (43) 26608-26615; first published October 12, 2020. https://doi.org/10.1073/pnas.2010849117
  
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Chemistry
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  A synthetic mimic of phosphodiesterase type 5 based on corona phase molecular recognition of single-walled carbon nanotubes
  Juyao Dong, Michael A. Lee, Ananth Govind Rajan, Imon Rahaman, Jessica H. Sun, Minkyung Park, Daniel P. Salem, and Michael S. Strano
  
  PNAS October 27, 2020 117 (43) 26616-26625; first published October 14, 2020. https://doi.org/10.1073/pnas.1920352117
  
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  Formation of an unusual glutamine tautomer in a blue light using flavin photocycle characterizes the light-adapted state
  Joshua J. Goings, Pengfei Li, Qiwen Zhu, and Sharon Hammes-Schiffer
  
  PNAS October 27, 2020 117 (43) 26626-26632; first published October 9, 2020. https://doi.org/10.1073/pnas.2016719117
  
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  A deltamethrin crystal polymorph for more effective malaria control
  Jingxiang Yang, Bryan Erriah, Chunhua T. Hu, Ethan Reiter, Xiaolong Zhu, Vilmalí López-Mejías, Isis Paola Carmona-Sepúlveda, Michael D. Ward, and Bart Kahr
  
  PNAS October 27, 2020 117 (43) 26633-26638; first published October 12, 2020. https://doi.org/10.1073/pnas.2013390117
  
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Computer Sciences
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  Physics successfully implements Lagrange multiplier optimization
  Sri Krishna Vadlamani, Tianyao Patrick Xiao, and Eli Yablonovitch
  
  PNAS October 27, 2020 117 (43) 26639-26650; first published October 12, 2020. https://doi.org/10.1073/pnas.2015192117
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Earth, Atmospheric, and Planetary Sciences
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  Reconciling the climate and ozone response to the 1257 CE Mount Samalas eruption
  David C. Wade, Céline M. Vidal, N. Luke Abraham, Sandip Dhomse, Paul T. Griffiths, James Keeble, Graham Mann, Lauren Marshall, Anja Schmidt, and Alexander T. Archibald
  
  PNAS October 27, 2020 117 (43) 26651-26659; first published October 12, 2020. https://doi.org/10.1073/pnas.1919807117
  
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Engineering
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  In situ bone regeneration of large cranial defects using synthetic ceramic implants with a tailored composition and design
  Omar Omar, Thomas Engstrand, Lars Kihlström Burenstam Linder, Jonas Åberg, Furqan A. Shah, Anders Palmquist, Ulrik Birgersson, Ibrahim Elgali, Michael Pujari-Palmer, Håkan Engqvist, and Peter Thomsen
  
  PNAS October 27, 2020 117 (43) 26660-26671; first published October 12, 2020. https://doi.org/10.1073/pnas.2007635117
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  Design rules for liquid crystalline electrolytes for enabling dendrite-free lithium metal batteries
  
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  Zeeshan Ahmad, Zijian Hong, and Venkatasubramanian Viswanathan
  
  PNAS October 27, 2020 117 (43) 26672-26680; first published October 9, 2020. https://doi.org/10.1073/pnas.2008841117
  
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Environmental Sciences
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  Large and seasonally varying biospheric CO₂ fluxes in the Los Angeles megacity revealed by atmospheric radiocarbon
  John B. Miller, Scott J. Lehman, Kristal R. Verhulst, Charles E. Miller, Riley M. Duren, Vineet Yadav, Sally Newman, and Christopher D. Sloop
  
  PNAS October 27, 2020 117 (43) 26681-26687; first published October 12, 2020. https://doi.org/10.1073/pnas.2005253117
  
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Physics
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  Photon-level broadband spectroscopy and interferometry with two frequency combs
  Nathalie Picqué and Theodor W. Hänsch
  
  PNAS October 27, 2020 117 (43) 26688-26691; first published October 14, 2020. https://doi.org/10.1073/pnas.2010878117
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Biological Sciences

Applied Biological Sciences
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  A synthetic mimic of phosphodiesterase type 5 based on corona phase molecular recognition of single-walled carbon nanotubes
  Juyao Dong, Michael A. Lee, Ananth Govind Rajan, Imon Rahaman, Jessica H. Sun, Minkyung Park, Daniel P. Salem, and Michael S. Strano
  
  PNAS October 27, 2020 117 (43) 26616-26625; first published October 14, 2020. https://doi.org/10.1073/pnas.1920352117
  
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  In situ bone regeneration of large cranial defects using synthetic ceramic implants with a tailored composition and design
  Omar Omar, Thomas Engstrand, Lars Kihlström Burenstam Linder, Jonas Åberg, Furqan A. Shah, Anders Palmquist, Ulrik Birgersson, Ibrahim Elgali, Michael Pujari-Palmer, Håkan Engqvist, and Peter Thomsen
  
  PNAS October 27, 2020 117 (43) 26660-26671; first published October 12, 2020. https://doi.org/10.1073/pnas.2007635117
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  In vivo mRNA display enables large-scale proteomics by next generation sequencing
  Panos Oikonomou, Roberto Salatino, and Saeed Tavazoie
  
  PNAS October 27, 2020 117 (43) 26710-26718; first published October 9, 2020. https://doi.org/10.1073/pnas.2002650117
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Biochemistry
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  Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10
  Han Feng, Huabin Tian, Yong Wang, Qixiang Zhang, Ni Lin, Songqing Liu, Yang Yu, Hongyu Deng, and Pu Gao
  
  PNAS October 27, 2020 117 (43) 26719-26727; first published October 8, 2020. https://doi.org/10.1073/pnas.2007774117
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  Cyclic peptides can engage a single binding pocket through highly divergent modes
  Karishma Patel, Louise J. Walport, James L. Walshe, Paul D. Solomon, Jason K. K. Low, Daniel H. Tran, Kevork S. Mouradian, Ana P. G. Silva, Lorna Wilkinson-White, Alexander Norman, Charlotte Franck, Jacqueline M. Matthews, J. Mitchell Guss, Richard J. Payne, Toby Passioura, Hiroaki Suga, and Joel P. Mackay
  
  PNAS October 27, 2020 117 (43) 26728-26738; first published October 12, 2020. https://doi.org/10.1073/pnas.2003086117
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  Structural basis for CDK7 activation by MAT1 and Cyclin H
  Stefan Peissert, Andreas Schlosser, Rafaela Kendel, Jochen Kuper, and Caroline Kisker
  
  PNAS October 27, 2020 117 (43) 26739-26748; first published October 14, 2020. https://doi.org/10.1073/pnas.2010885117
  
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  The cryoelectron microscopy structure of the human CDK-activating kinase
  - Aug 27, 2020
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Biophysics and Computational Biology
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  Formation of an unusual glutamine tautomer in a blue light using flavin photocycle characterizes the light-adapted state
  Joshua J. Goings, Pengfei Li, Qiwen Zhu, and Sharon Hammes-Schiffer
  
  PNAS October 27, 2020 117 (43) 26626-26632; first published October 9, 2020. https://doi.org/10.1073/pnas.2016719117
  
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  One-dimensional spatial patterning along mitotic chromosomes: A mechanical basis for macroscopic morphogenesis
  Lingluo Chu, Zhangyi Liang, Maria V. Mukhina, Jay K. Fisher, John W. Hutchinson, and Nancy E. Kleckner
  
  PNAS October 27, 2020 117 (43) 26749-26755; first published October 13, 2020. https://doi.org/10.1073/pnas.2013709117
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  Vimentin filaments drive migratory persistence in polyploidal cancer cells
  
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  Botai Xuan, Deepraj Ghosh, Joy Jiang, Rachelle Shao, and Michelle R. Dawson
  
  PNAS October 27, 2020 117 (43) 26756-26765; first published October 12, 2020. https://doi.org/10.1073/pnas.2011912117
  
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  Motile ghosts of the halophilic archaeon, Haloferax volcanii
  
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  Yoshiaki Kinosita, Nagisa Mikami, Zhengqun Li, Frank Braun, Tessa E. F. Quax, Chris van der Does, Robert Ishmukhametov, Sonja-Verena Albers, and Richard M. Berry
  
  PNAS October 27, 2020 117 (43) 26766-26772; first published October 13, 2020. https://doi.org/10.1073/pnas.2009814117
  
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Cell Biology
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  The eukaryotic translation initiation factor eIF4E elevates steady-state m⁷G capping of coding and noncoding transcripts
  Biljana Culjkovic-Kraljacic, Lucy Skrabanek, Maria V. Revuelta, Jadwiga Gasiorek, Victoria H. Cowling, Leandro Cerchietti, and Katherine L. B. Borden
  
  PNAS October 27, 2020 117 (43) 26773-26783; first published October 14, 2020. https://doi.org/10.1073/pnas.2002360117
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  The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1
  Daniel Hamaoui, Mathilde M. Cossé, Jagan Mohan, Alf Håkon Lystad, Thomas Wollert, and Agathe Subtil
  
  PNAS October 27, 2020 117 (43) 26784-26794; first published October 14, 2020. https://doi.org/10.1073/pnas.2005389117
  
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  p31^comet promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase
  
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  Prabha Sarangi, Connor S. Clairmont, Lucas D. Galli, Lisa A. Moreau, and Alan D. D’Andrea
  
  PNAS October 27, 2020 117 (43) 26795-26803; first published October 13, 2020. https://doi.org/10.1073/pnas.2008830117
  
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  p31^comet and TRIP13 recycle Rev7 to regulate DNA repair
  - Oct 29, 2020
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  Functional interplay among thiol-based redox signaling, metabolism, and ferroptosis unveiled by a genetic variant of TP53
  Julia I-Ju Leu, Maureen E. Murphy, and Donna L. George
  
  PNAS October 27, 2020 117 (43) 26804-26811; first published October 14, 2020. https://doi.org/10.1073/pnas.2009943117
  
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Developmental Biology
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  Two classes of active transcription sites and their roles in developmental regulation
  Sarah Robinson-Thiewes, John McCloskey, and Judith Kimble
  
  PNAS October 27, 2020 117 (43) 26812-26821; first published October 8, 2020. https://doi.org/10.1073/pnas.2013163117
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  Multiscale imaging of basal cell dynamics in the functionally mature mammary gland
  
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  Alexander J. Stevenson, Gilles Vanwalleghem, Teneale A. Stewart, Nicholas D. Condon, Bethan Lloyd-Lewis, Natascia Marino, James W. Putney, Ethan K. Scott, Adam D. Ewing, and Felicity M. Davis
  
  PNAS October 27, 2020 117 (43) 26822-26832; first published October 8, 2020. https://doi.org/10.1073/pnas.2016905117
  
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Ecology
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  Bird populations and species lost to Late Quaternary environmental change and human impact in the Bahamas
  
  From the Cover
  
  David W. Steadman and Janet Franklin
  
  PNAS October 27, 2020 117 (43) 26833-26841; first published October 5, 2020. https://doi.org/10.1073/pnas.2013368117
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  Human disturbance increases trophic niche overlap in terrestrial carnivore communities
  Philip J. Manlick and Jonathan N. Pauli
  
  PNAS October 27, 2020 117 (43) 26842-26848; first published October 12, 2020. https://doi.org/10.1073/pnas.2012774117
  
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  Phylogenetic escape from pests reduces pesticides on some crop plants
  Ian S. Pearse and Jay A. Rosenheim
  
  PNAS October 27, 2020 117 (43) 26849-26853; first published October 12, 2020. https://doi.org/10.1073/pnas.2013751117
  
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  Pest pressure relates to similarity of crops and native plants
  - Nov 09, 2020
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  Interspecific competition slows range expansion and shapes range boundaries
  Geoffrey Legault, Matthew E. Bitters, Alan Hastings, and Brett A. Melbourne
  
  PNAS October 27, 2020 117 (43) 26854-26860; first published October 14, 2020. https://doi.org/10.1073/pnas.2009701117
  
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Evolution
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  The earliest-known mammaliaform fossil from Greenland sheds light on origin of mammals
  
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  Tomasz Sulej, Grzegorz Krzesiński, Mateusz Tałanda, Andrzej S. Wolniewicz, Błażej Błażejowski, Niels Bonde, Piotr Gutowski, Maksymilian Sienkiewicz, and Grzegorz Niedźwiedzki
  
  PNAS October 27, 2020 117 (43) 26861-26867; first published October 12, 2020. https://doi.org/10.1073/pnas.2012437117
  
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  Horizontal gene transfer potentiates adaptation by reducing selective constraints on the spread of genetic variation
  Laura C. Woods, Rebecca J. Gorrell, Frank Taylor, Tim Connallon, Terry Kwok, and Michael J. McDonald
  
  PNAS October 27, 2020 117 (43) 26868-26875; first published October 14, 2020. https://doi.org/10.1073/pnas.2005331117
  
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Genetics
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  Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast
  Nicole Stantial, Anna Rogojina, Matthew Gilbertson, Yilun Sun, Hannah Miles, Samantha Shaltz, James Berger, Karin C. Nitiss, Sue Jinks-Robertson, and John L. Nitiss
  
  PNAS October 27, 2020 117 (43) 26876-26884; first published October 12, 2020. https://doi.org/10.1073/pnas.2008721117
  
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Immunology and Inflammation
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  Poxvirus-encoded TNF receptor homolog dampens inflammation and protects from uncontrolled lung pathology during respiratory infection
  Zahrah Al Rumaih, Ma. Junaliah Tuazon Kels, Esther Ng, Pratikshya Pandey, Sergio M. Pontejo, Alí Alejo, Antonio Alcamí, Geeta Chaudhri, and Gunasegaran Karupiah
  
  PNAS October 27, 2020 117 (43) 26885-26894; first published October 12, 2020. https://doi.org/10.1073/pnas.2004688117
  
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  TNF deficiency dysregulates inflammatory cytokine production, leading to lung pathology and death during respiratory poxvirus infection
  - Jun 22, 2020
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  TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin
  Lee Swanson, Gajanan D. Katkar, Julian Tam, Rama F. Pranadinata, Yogitha Chareddy, Jane Coates, Mahitha Shree Anandachar, Vanessa Castillo, Joshua Olson, Victor Nizet, Irina Kufareva, Soumita Das, and Pradipta Ghosh
  
  PNAS October 27, 2020 117 (43) 26895-26906; first published October 14, 2020. https://doi.org/10.1073/pnas.2011667117
  
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Microbiology
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  The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli
  Jacqueline Grimm, Handuo Shi, Wei Wang, Angela M. Mitchell, Ned S. Wingreen, Kerwyn Casey Huang, and Thomas J. Silhavy
  
  PNAS October 27, 2020 117 (43) 26907-26914; first published October 12, 2020. https://doi.org/10.1073/pnas.2015556117
  
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  Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection
  Caitlin E. Edwards, Boyd L. Yount, Rachel L. Graham, Sarah R. Leist, Yixuan J. Hou, Kenneth H. Dinnon III, Amy C. Sims, Jesica Swanstrom, Kendra Gully, Trevor D. Scobey, Michelle R. Cooley, Caroline G. Currie, Scott H. Randell, and Ralph S. Baric
  
  PNAS October 27, 2020 117 (43) 26915-26925; first published October 12, 2020. https://doi.org/10.1073/pnas.2001046117
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  Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity
  Daniel W. Heindel, Sujeethraj Koppolu, Yue Zhang, Brian Kasper, Lawrence Meche, Christopher A. Vaiana, Stephanie J. Bissel, Chalise E. Carter, Alyson A. Kelvin, Mohamed Elaish, Joaquin Lopez-Orozco, Bin Zhang, Bin Zhou, Tsui-Wen Chou, Lauren Lashua, Tom C. Hobman, Ted M. Ross, Elodie Ghedin, and Lara K. Mahal
  
  PNAS October 27, 2020 117 (43) 26926-26935; first published October 12, 2020. https://doi.org/10.1073/pnas.2008203117
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  Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties
  Osmar N. Silva, Marcelo D. T. Torres, Jicong Cao, Elaine S. F. Alves, Leticia V. Rodrigues, Jarbas M. Resende, Luciano M. Lião, William F. Porto, Isabel C. M. Fensterseifer, Timothy K. Lu, Octavio L. Franco, and Cesar de la Fuente-Nunez
  
  PNAS October 27, 2020 117 (43) 26936-26945; first published October 12, 2020. https://doi.org/10.1073/pnas.2012379117
  
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  Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases
  Michael K. Lo, César G. Albariño, Jason K. Perry, Silvia Chang, Egor P. Tchesnokov, Lisa Guerrero, Ayan Chakrabarti, Punya Shrivastava-Ranjan, Payel Chatterjee, Laura K. McMullan, Ross Martin, Robert Jordan, Matthias Götte, Joel M. Montgomery, Stuart T. Nichol, Mike Flint, Danielle Porter, and Christina F. Spiropoulou
  
  PNAS October 27, 2020 117 (43) 26946-26954; first published October 7, 2020. https://doi.org/10.1073/pnas.2012294117
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  Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity
  Suzanne J. F. Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan ter Horst, Laurens Liesenborghs, Bart Hens, Valentijn Vergote, Elisabeth Heylen, Karine Barthelemy, Elke Maas, Carolien De Keyzer, Lindsey Bervoets, Jasper Rymenants, Tina Van Buyten, Xin Zhang, Rana Abdelnabi, Juanita Pang, Rachel Williams, Hendrik Jan Thibaut, Kai Dallmeier, Robbert Boudewijns, Jens Wouters, Patrick Augustijns, Nick Verougstraete, Christopher Cawthorne, Judith Breuer, Caroline Solas, Birgit Weynand, Pieter Annaert, Isabel Spriet, Greetje Vande Velde, Johan Neyts, Joana Rocha-Pereira, and Leen Delang
  
  PNAS October 27, 2020 117 (43) 26955-26965; first published October 9, 2020. https://doi.org/10.1073/pnas.2014441117
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Neuroscience
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  Theory of neuronal perturbome in cortical networks
  Sadra Sadeh and Claudia Clopath
  
  PNAS October 27, 2020 117 (43) 26966-26976; first published October 14, 2020. https://doi.org/10.1073/pnas.2004568117
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  Nucleus accumbens cytoarchitecture predicts weight gain in children
  Kristina M. Rapuano, Jennifer S. Laurent, Donald J. Hagler Jr, Sean N. Hatton, Wesley K. Thompson, Terry L. Jernigan, Anders M. Dale, B. J. Casey, and Richard Watts
  
  PNAS October 27, 2020 117 (43) 26977-26984; first published October 12, 2020. https://doi.org/10.1073/pnas.2007918117
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  Regulating quantal size of neurotransmitter release through a GPCR voltage sensor
  
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  Quanfeng Zhang, Bing Liu, Yinglin Li, Lili Yin, Muhammad Younus, Xiaohan Jiang, Zhaohan Lin, Xiaoxuan Sun, Rong Huang, Bin Liu, Qihui Wu, Feipeng Zhu, and Zhuan Zhou
  
  PNAS October 27, 2020 117 (43) 26985-26995; first published October 12, 2020. https://doi.org/10.1073/pnas.2005274117
  
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  Rhodopsin-mediated light-off-induced protein kinase A activation in mouse rod photoreceptor cells
  
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  Shinya Sato, Takahiro Yamashita, and Michiyuki Matsuda
  
  PNAS October 27, 2020 117 (43) 26996-27003; first published October 12, 2020. https://doi.org/10.1073/pnas.2009164117
  
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  Spatial organization of functional clusters representing reward and movement information in the striatal direct and indirect pathways
  Jung Hwan Shin, Min Song, Se-Bum Paik, and Min Whan Jung
  
  PNAS October 27, 2020 117 (43) 27004-27015; first published October 14, 2020. https://doi.org/10.1073/pnas.2010361117
  
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Pharmacology
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  Coupling stabilizers open K_V1-type potassium channels
  Malin Silverå Ejneby, Björn Wallner, and Fredrik Elinder
  
  PNAS October 27, 2020 117 (43) 27016-27021; first published October 13, 2020. https://doi.org/10.1073/pnas.2007965117
  
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Physiology
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  Contractile pericytes determine the direction of blood flow at capillary junctions
  
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  Albert L. Gonzales, Nicholas R. Klug, Arash Moshkforoush, Jane C. Lee, Frank K. Lee, Bo Shui, Nikolaos M. Tsoukias, Michael I. Kotlikoff, David Hill-Eubanks, and Mark T. Nelson
  
  PNAS October 27, 2020 117 (43) 27022-27033; first published October 13, 2020. https://doi.org/10.1073/pnas.1922755117
  
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Plant Biology
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  EXO70D isoforms mediate selective autophagic degradation of type-A ARR proteins to regulate cytokinin sensitivity
  Atiako Kwame Acheampong, Carly Shanks, Chia-Yi Cheng, G. Eric Schaller, Yasin Dagdas, and Joseph J. Kieber
  
  PNAS October 27, 2020 117 (43) 27034-27043; first published October 13, 2020. https://doi.org/10.1073/pnas.2013161117
  
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  Loss of the common immune coreceptor BAK1 leads to NLR-dependent cell death
  Yujun Wu, Yang Gao, Yanyan Zhan, Hong Kui, Hongyan Liu, Li Yan, Birgit Kemmerling, Jian-Min Zhou, Kai He, and Jia Li
  
  PNAS October 27, 2020 117 (43) 27044-27053; first published October 14, 2020. https://doi.org/10.1073/pnas.1915339117
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Population Biology
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  Sociopolitical stress and acute cardiovascular disease hospitalizations around the 2016 presidential election
  Matthew T. Mefford, Murray A. Mittleman, Bonnie H. Li, Lei X. Qian, Kristi Reynolds, Hui Zhou, Teresa N. Harrison, Alan C. Geller, Stephen Sidney, Richard P. Sloan, Elizabeth Mostofsky, and David R. Williams
  
  PNAS October 27, 2020 117 (43) 27054-27058; first published October 12, 2020. https://doi.org/10.1073/pnas.2012096117
  
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Sustainability Science
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  A deltamethrin crystal polymorph for more effective malaria control
  Jingxiang Yang, Bryan Erriah, Chunhua T. Hu, Ethan Reiter, Xiaolong Zhu, Vilmalí López-Mejías, Isis Paola Carmona-Sepúlveda, Michael D. Ward, and Bart Kahr
  
  PNAS October 27, 2020 117 (43) 26633-26638; first published October 12, 2020. https://doi.org/10.1073/pnas.2013390117
  
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Corrections

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Correction for Altschul et al., Opinion: To understand how migrations affect human securities, look to the past
PNAS October 27, 2020 117 (43) 27059; first published October 12, 2020. https://doi.org/10.1073/pnas.2019458117
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Correction for Fraser, Detecting selection with a genetic cross
PNAS October 27, 2020 117 (43) 27060; first published October 12, 2020. https://doi.org/10.1073/pnas.2019693117
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Correction for Yang et al., Accumulation of high-value bioproducts in planta can improve the economics of advanced biofuels
PNAS October 27, 2020 117 (43) 27061; first published October 12, 2020. https://doi.org/10.1073/pnas.2018562117
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SI Correction

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Correction to Supporting Information for Li et al., Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes
PNAS October 27, 2020 117 (43) 27062; first published October 12, 2020. https://doi.org/10.1073/pnas.2019025117
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